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viagra (sildenafil)

The preparation recovers the normal reaction to sexual arousal

viagra (sildenafil)

Pharmacological action:

The preparation recovers the normal reaction to sexual arousal. A physiological mechanism that ensures an erection is not possible without emitting of nitric oxide in cavernous body during sexual stimulation. NO activates a special enzyme called guanylate cyclase, as a result the level of cycle guanosine monophosphate (cGMP) is increased, muscles of the cavernous body relax and the blood flow is increased in a penis. Sildenafil, the active ingredient of VIAGRA, is selective inhibitor of PDE5 (phosphodiesterase type 5) that ensures the collapse of cGMP in the cavernous body. The drug is characterized by a peripheral effect on penile erection. It is noteworthy that sildenafil relaxes the cavernous body not directly, but by means of relaxing function of nitric oxide. It is known that the sexual stimulation is needed for a useful pharmacological action. The drug is well tolerated, healthy volunteers did not reported about clinically significant deviations at single taking in amount not more than 100 mg.

Indication for use:

The drug is prescribed at erectile dysfunctions (as a rule, psychogenic, organic and mixed).

Method of use:

Tablets are taken orally, approximately one hour before planned sexual intercourse. The optimal single dose for adults is 50 mg once a day. Taking into consideration the individual tolerance and efficacy of the drug, the dose may be reduced to 25 mg or increased to 100 mg. The maximum single dose is 100 mg per day. The standard dose should not be changed for elderly.

Side effects:

The medicine is well tolerated. In some cases were observed side effects:

  • central nervous system (insomnia, dizziness and rise of muscular tonus)
  • cardio-vascular system (afflux, headache, vasodilation)
  • musculoskeletal system (pain in the joints and muscles)
  • gastrointestinal tract (nausea, diarrhea, dyspepsia)
  • skin (rash)
  • sensory organs (conjunctivitis, violation of vision clarity, increased light perception, change of color perception)
  • organs of the respiratory system (respiratory distress, pharyngitis, sinusitis, rhinitis, nasal congestion, respiratory tract infection)
  • urogenital system (disorder of prostate, infection urinary channels)

Other side effects included symptoms of influenza, back pain or stomach. Cases of priapism were reported rare.

Contraindications:

The medicine is contraindicated to patients with hypersensivity to the components of the medicine and with the deformation of a penis (Peyronie's disease, cavernous fibrosis, angulation). Also this drug should not be taken in the following disorders:

  • increased tendency to bleeding
  • acute stage of ulcer disease of the gastrointestinal tract
  • disorders of the liver, especially severe renal failure or cirrhosis
  • diseases that develop priapism, including leukemia, multiple myeloma and sickle cell anemia
  • severe hypotension or hypertension
  • various heart diseases, including unstable angina, arrhythmia in dangerous form and cardiac insufficiency

If the patient has suffered stroke or myocardial infarction, the drug should not be used the next six months. Also, Viagra is not administered to children. It is strictly forbidden simultaneously using this drug with nitrates and donors of nitric oxide. Viagra should not be prescribed to men whom are contraindicated sexual activity.

Pregnancy:

This drug is not prescribed to women. As the result of the reproductive experiments on rabbits and rats it was revealed that there is no teratogenic effect of Viagra. The fetus has developed without deviations and disorders. Also the morphology and activity of sperm of volunteers was investigated at a single dose of the drug taking. No deviations have been found.

Interaction with other medicines:

The administration of erythromycin, cimetidine and ketoconazole is characterized by decrease of clearance and subsequent increase of sildenafil content in blood plasma. Coadministration of Viagra and sodium nitroprusside enhances its antiaggregant (antiplatelet) effect. Viagra enhances the hypotensive effect of drugs containing nitrates. This may lead to death. Also dangerous to life simultaneous reception of the drug with oral hypoglycemic drugs, calcium channel inhibitors and beta- adrenoceptor blocking drugs.

Viagra 25 mg

The main distinguishing feature of the drug from similar drugs is its effectiveness for the elderly. A dosage of 25 mg is ideal for representatives of the male sex. Sildenafil does not cause any harm to the health of this age group, but it guarantees the desired erection.

Viagra 50 mg

The drug Sildenafil 50mg perfectly copes with the problems of the male reproductive system, providing a quality erection. In this case, the effect occurs only if a man has a sexual desire for a partner. It is not recommended to use more than 50 mg of the drug per day, but in some cases, if there is no proper result, you can increase the dose by 25 mg or 50 mg. However, it is strictly forbidden to exceed 100 mg. If you do not comply with this recommendation, there may be negative side effects on the body. The drug is taken half an hour before sexual intercourse. It is strongly recommended to additionally receive expert advice, especially in such cases:

Viagra 100 mg

Even in the most difficult cases, taking Sildenafil 100mg allows you to achieve a good erection. This feature is one of the main advantages of the drug. It also does an excellent job when the patient is suffering from diabetes mellitus, has spinal cord injuries, and there have ever been surgeries on the prostate gland. This is really a new generation of drugs, which has many advantages.

Viagra 150 mg

The drug Sildenafil 150mg has a great effectiveness, which is clinically proven. The product is medicinal and affects the male reproductive system, while ensuring proper erection. The drug is popular among consumers, but pharmacies the price is very high. However, there is an opportunity to purchase an analogue with an equivalent chemical composition that has passed clinical tests; this is a generic Sildenafil 150mg.

Viagra 200 mg

Sildenafil with enhanced action will help to cope with sexual dysfunction in those men for whom 100 mg of the drug is not sufficient dose. If you take 200 mg of medicine, you are guaranteed to get a positive result. An erection will occur naturally; Sildenafil will only start some processes. Side effects rarely occur during drug use, which determines the high demand for the product.

Viagra professional

Sildenafil Professional in a dosage of 50 mg does not belong to hormonal drugs. It is possible to achieve a positive effect thanks to the impact on humoral mechanisms. The drug increases blood flow to the penis. It has a selective effect: it affects exclusively the reproductive system. Other organs and systems are not involved in this process. This distinguishes Sildenafil Professional from impotence medications, which cause side effects.

Viagra soft

Sildenafil Soft is ideal for solving such a painful and delicate problem as impotence. The effectiveness of this drug has been proven by numerous clinical trials. Its advantage is the speed of action onset. It is significantly better than that of analog medical drugs. The drug is available in the form of pills for dissolving in mouth.

Viagra super active

One of the improved medical drugs for treating male problems associated with potency is Viagra Super Active 100. In addition to the usual Viagra composition, it also includes medicinal herbs that enhance the effect, increase the time and productivity of sexual intercourse. It is available in gelatin capsules, which have a good effect on the gastrointestinal tract, excluding heartburn or other uncomfortable problems associated with the stomach. It is well and quickly absorbed and acts for a long time.

Overdose:

The research has shown that the adverse effects were manifested more obviously at the overdose. Only symptomatic therapy can be applied for the treatment. Dialysis is not effective because the active ingredient actively and rapidly is bound with the proteins of blood plasma.

Delivery form:

Viagra is produced in the form of firm-coated tablets. The tablets are in the aluminum blister that is in carton package.

Storage conditions:

Viagra should be stored in a cool dry place, away from children. The storage temperature should not exceed 30 °C. The shelf-life is 2 years. It is prohibited to administrate expired medicine.

Synonyms:

Sildenafil

Ingredients:

Main active ingredient is Sildenafil in the form of citrate. The inactive ingredients are anhydrous calcium phosphate, magnesium stearate, croscarmellose sodium, titanium dioxide (E 171), triacetin, hypromellose, FD&C Blue aluminum lake (E 132), lactose.

Additionaly:

The drug is put on prescription.

Attention!

The description of the medicine Viagra at this page is the simplified and supplemented version of the official instructions. In any case you should consult a doctor and to read carefully the instructions of the producer before use of the preparation. The information about the medicine is presented only for the purpose of familiarization and cannot be used as the instructions for self-treatment. Only a doctor is authorized to prescribe the medicine and also to determine the dose and method of use.